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KMID : 0387420080190030195
Korean Society of Oriental Neuropsychiatry
2008 Volume.19 No. 3 p.195 ~ p.203
A Clinical Study to Assess the Safety of GyoGam-Dan
Kang Hyung-Won

Kim Ji-Hwon
Kim Jin-Heong
Lee Chung-Sik
Lee Sang-Eon
Kim Dae-Hyun
Kim Tae-Heon
Abstract
Objective: ¡¯GyoGam-Dan¡¯ is known as a medicine to cure depression in Donguibogam (traditional Korean oriental medicine book). GyoGam-dan which is composed of Cyperi Rhizoma L. and Poria cum Radix pini has been used by basic prescription of asymptom related to all kinds of Qi(Ѩ) disease. Although it has been clinically used for a long time, its safety have never been proved till now.

Methods: We had collected data of 610 cases of patients taking ¡¯GyoGam-Dan¡¯ at Wonkwang univ. oriental medical center for a period of three years (2005.3.09-2008.04.30). On the patients¡¯ blood, the levels of LFT and RFT were examined and the residual levels of heavy metals and pesticides were measured.

Results: There were 610 patients who had taken GyoGam-Dan for about three years. In the patients, the most common diseases is depression, followed by palpitation, and then insomnia. Among the patients¡¯ estimations on its effectiveness, there were many of positive ones. The blood analyses of patients who had taken GyoGam-Dan did not show any problems and moreover there was not any problems in the levels of residual heavy metals and agricultural pesticides. Taken together, GyoGam-Dan was proved to be a safe medicine for health.

Conclusions: Our clinical and chemical studies show that GyoGam-dan has the anti-stress effect and is a safe medicine of which side effect does not exist. Hereafter, Nigorous clinical trial on GyoGam-dan is required.
KEYWORD
GyoGam-Dan, Anti-Stress Effects, Herbal medicine
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